In the last ten years, I built an informal research group, which at present includes 17 researchers. We develop methods for constraint-based data mining, predicting structured outputs, and automated modelling of dynamics systems and apply them to problems from systems biology and ecology.I coordinated the project IQ, which produced a general framework for data mining, leading to representational ontologies for datatypes and data mining) and methodological advances (methods for predicting structured outputs based on constrained predictive clustering). I participated in two EU-funded projects in the area of systems biology (E.E.T. Pipeline, PHAGOSYS).